Umbilical Plaque in Psoriatic Arthritis

نویسندگان

  • Takao Nagashima
  • Seiji Minota
چکیده

A 68-year-old man was referred to us with glucocorticoidresistant polyarthralgia. Three months before presentation, he received a tentative diagnosis of polymyalgia rheumatica and was treated with prednisolone (10 mg/day) by an orthopedic surgeon. The findings for rheumatoid factor and anticitrullinated peptide antibody were negative. After his polyarthralgia improved, the prednisolone was gradually tapered, but the polyarthralgia soon recurred. Readministration of prednisolone was less effective the second time. His C-reactive protein level was 3.5 mg/dL under treatment with prednisolone at 10 mg/day. On examination, he had pain in the neck and right shoulder joint and arthritis of the right ankle, as well as a rash resembling seborrheic dermatitis at his hairline. After removing his shirt, a large, thick, pink-whitish plaque was seen at the umbilicus (Picture 1). In addition, there was a red-purple scaly rash on his back (Picture 2), and the nail of his right thumb was yellow (Picture 3). A dermatologist diagnosed the patient to have psoriasis. We therefore diagnosed the joint involvement as being due to psoriatic arthritis (1). After treatment with adalimumab, his joint symptoms and skin lesions gradually improved.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Depression and quality of life in psoriasis and psoriatic arthritis patients

ackground: Psoriasis is a chronic hyperproliferative disease of the skin, scalp, nails, and joints that affects 2% of the general population. One of the extracutaneous manifestations of psoriasis is psoriatic arthritis which occurs in 25–34% of the psoriasis cases. This type of inflammatory arthritis is characterized by pain, swelling, and tenderness around the joints, and may adversely a...

متن کامل

بررسی سطح اسید اوریک سرم در بیماران مبتلا به پسوریازیس

Background: Psoriasis is a common, chronic disease of the skin, in which both genetic and environmental factors play a critical role. The most characteristic lesions consist of red, scaly plaques present particularly over extensor surfaces and scalp. Studies have reported association between psoriasis and many other diseases in both cutaneous and systemic forms of the disease. Several studies w...

متن کامل

The prevalence of psoriatic arthritis in psoriatic patients in Tehran, Iran.

BACKGROUND Psoriatic arthritis is an inflammatory arthritis which is associated with psoriasis. There is no general agreement in the literature regarding the epidemiology of psoriatic arthritis. In this study, we evaluated the prevalence of psoriatic arthritis in a relatively large number of psoriatic patients. METHODS Three hundred and twenty patients with psoriasis were evaluated in a cross...

متن کامل

Umbilical cord blood stem cell treatment for a patient with psoriatic arthritis

Clinical and laboratory results document psoriatic arthritis in a 56-year old patient. The symptoms did not resolve with standard treatments (nonsteroidal anti-inflammatory drugs, steroids and methotrexate). TNF-alpha inhibitors (certolizumab pegol and adalimumab) were added to the treatment regime, with some adverse effects. A trial of human umbilical cord stem cell therapy was then initiated....

متن کامل

Biologics for Psoriasis and Psoriatic Arthritis

The purposes of this updated review of antipsoriatic biologic agents are to compare their pharmacologic properties and evaluate studies that address certain key clinical questions that are pertinent to the development of criteria for use of biologic agents for chronic plaque psoriasis (CPP) and psoriatic arthritis (PsA) in the Veterans Health Administration. No studies involving a U.S. Veteran ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 56  شماره 

صفحات  -

تاریخ انتشار 2017